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How To Usetake Methylprednisolone By Mouth With Or Without Food As Directed By Your Doctor.take The Exact Quantity Of Methylprednisolone As Prescribed By The Doctor.take Methylprednisolone Regularly To Get The Most Benefit From It.to Help Remember, Take Methylprednisolone At The Same Time Every Day.quantity Is Based On Your Medical Condition And Response To Treatment.do Not Increase Your Quantity Or Take This Product More Often Than Directed.expert Advicetake This Medication With Meals Or Milk.gradually Lower The Dose, Do Not Stop The Medication Abruptly.\xa0avoid Alcohol During Therapy.\xa0diabetic Patients Should Check Their Glucose Levels Regularly.\xa0consult Your Doctor/prescriber For Dietery Instructions.